• Course Syllabus - course contents, rules, links, and other info
  
• Canvas - homework, solutions, grades, discussions.

R corner

      R labs

• Lab 1. First steps in R
• Lab 2. Power analysis with asbio
• Lab 3. Survival Analysis
• Lab 4. Randomized designs
• Lab 5. Two-stage designs
• Lab 6. Sequential clinical trials - Binomial example
• Lab 7. Group sequential clinical trials
• Lab 8. Epidemiology: risks and continugency tables

      Data Sets

• Cardiac patients data: Hearts.csv, Hearts.rda
• Brain cancer patients: BrainCancer.csv, BrainCancer.rda
• Government shutdown-2025: shutdowns.csv and its analysis with the Kaplan-Meier and Cox methods

Handouts

      Review of basic probability

• Rules of Probability (slides)
• Random variables, expected value, variance (slides)
• Normal distribution, calculation of Normal probabilities, and the distribution of a sample mean (slides)

      Review of basic statistics

• Detailed review of descriptive statistics
• Detailed review of estimation and hypothesis testing
•       Very short review of estimation and hypothesis testing
•       Slides on confidence intervals
•       Slides on hypothesis testing
•       Slides on two-sample hypotheses and confidence intervals
•       Review of p-values
• Slides on ANOVA
• Detailed review of regression
•       Slides on regression

      Tables

• Table of random numbers
• Table of Normal distribution
• Table of T-distribution
• Table of Chi-Square distribution
• Table of F distribution
•       Short tables of Normal, T, and F distributions (for quizzes)
• Table of Binomial distribution
• Table of Beta distribution
• Table of Gamma distribution

Related Articles

• Clinical trial of the Pfizer COVID vaccine - results and data
• Clinical trial of the Moderna COVID vaccine - results and data
• Colon cancer is rising in younger adults. Could extreme running be a factor? Published on Aug 25, 2025
• Clinical trial of Prometa (which was found inefficient)
• The conference that we hosted in 2019. Barry Nussbaum is an honoree.
• Barry Nussbaum and the story of unleaded gasoline - one of many articles about the historic experiment and a historic graph
• The conference in Sequential Methods that we are hosting at AU in June 2026
• Conversation with Allen Wallis about the beginning of sequential analysis